Mexico came into the Alamodome riding a 12-game unbeaten streak under manager Gerardo “Tata” Martino, but his former side emphatically halted that with an offensive outburst from which El Tri ultimately couldn’t recover.
Martinez, who plays for Inter Milan, repeatedly took advantage of sloppy Mexican defending during the first half. He slotted in his first in the 17th minute with a slick left-footed shot from just inside the box. He struck again five minutes after getting behind Mexico’s line, and added his third in the 39th minute after robbing the ball from Nestor Araujo.
Paris Saint-Germain’s Leandro Paredes scored Argentina’s other goal from the penalty spot in the 33rd minute.
Mexico had not conceded four goals since a 4-1 loss to Germany in the 2017 Confederations Cup semifinal in Russia.
Tuesday’s loss came after Mexico had dominated the United States last Friday in a 3-0 win.
Argentina, under Lionel Scaloni, finish the international break on a high note following a scoreless draw against continental rivals Chile last week.